How To Deal With Unused Embryos

By Annabelle Holman


When couples have difficulty conceiving a child by any other means, including artificial insemination, they may decide to try in vitro fertilization. In this process, the woman's eggs may be fertilized in the laboratory; the resulting embryos are then implanted into her uterus. Unused embryos that do not get implanted remain the responsibility of the parents from whose cells they are derived.

These spare embryos remain frozen and stored. With today's tissue-freezing methods, these spare embryos retain their viability for many, many years. The parents can decide to keep them in storage, pass them on to other childless couples who are unable to conceive or donate them for scientific research using stem cells. This is becoming an extremely popular process with couples who find themselves unable to produce their own embryos via in vitro fertilization. The parents of the excess embryos may also ultimately decide to discard them.

Stem cells are highly primitive cells that have the ability to differentiate into all other cell types in the body. This is what is meant by the term, "pluripotent." Stem cells are turning out to be incredibly useful for medical purposes, although they are very tightly regulated because of their potential for abuse.

Researchers at the University of Utah pioneered the procedure whereby a patient's own stem cells are injected into their left ventricle in an attempt to treat heart failure. At this point, they are called cardiac repair cells. They are derived from the patient's bone marrow and then cultured for just under fortnight, after which they are implanted into the heart. It turns out these cells are much hardier than the original cells that were harvested from the bone marrow.

Stem cells were first isolated from mice in 1981 and in humans in 1998. Some are derived from human embryos that were not used in IVF, although there are other sources. Stem cells may also be harvested from umbilical cords, bone marrow and peripheral blood. Stem cells have shown promise in treating many different medical conditions. These include cancer, neurological disorders and diabetes.

Bone marrow comes from rich deposits deep inside the larger bones of the human body, most notably the pelvic bone. This process is very painful so it is performed under a general anesthetic. A wide-bore needle is injected into the hip and then into the bone marrow from which the tissue is collected.

Typically, peripheral blood is not endowed with a plethora of stem cells. In this case, patients are prepared by giving them hormones called growth factors. This takes place a few days prior to harvesting. The actual collection process may take hours. Newborn blood is also rich in these cells. Some remain in the umbilical cord, which is set aside for future transplantation. To date, human umbilical cord cells have only been transplanted into small adults and children.

Once the couples who have been storing embryos are sure they no longer want any more children, their spare embryos may be donated to other couples, to scientific research or they may be ultimately destroyed.




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